Table 4: Laboratory parameters of severe COVID-19 patients with or without hepatitis virus infection.

Variable (unit, normal range)

Total

(n = 50)

With hepatitis virus infection (n = 24)

without hepatitis virus infection (n = 26)

P value

Platelets (109/L)

177.5(124.75~249.0)

173.5(117.75~211.25)

200.0(124.75~282.75)

0.248

Lymphocytes (109/L)

0.84(0.415~1.18)

0.59(0.43~1.06)

0.95(0.41~1.22)

0.252

CD3+ T cells (count/uL)

451(311.5~731.5)

384.5(258.0~746.75)

594.0(343.0~732.0)

0.403

CD3+CD4+ T cells (count/uL)

316.0(116.0~420.0)

249.0(103.0~427.25)

354.0(129.0~420.0)

0.687

CD3+CD8+ T cells (count/uL)

223.0(94.5~301.5)

127.5(78.25~314.0)

266.0(145.0~290.0)

0.267

CD19+ B cells (count/uL)

84(44~191.5)

75.0(40.50~148.0)

90.0(71.0~197.0)

0.373

PT (s)

12.4(11.8~13.56)

13.0(11.9~13.9)

12.3(11.75~13.05)

0.173

PT-INR

1.14(1.08~1.24)

1.19(1.09~1.27)

1.13(1.075~1.195)

0.166

CRP ((mg/L))

32.7(8.05~95.44)

29.47(6.81~97.79)

32.7(8.5~97.5)

0.803

PCT(ng/ml)

0.05(0.05~0.14)

0.05(0.05~0.07)

0.095(0.05~0.81)

0.078

LDH (U/L)

282(199.5~449.75)

292.0(200.5~456.5)

269.0(191.5~442.0)

0.831

NLR

4.84(2.57~13.7)

4.8(3.07~14.6)

5.2(2.39~11.99)

0.669

ALT (U/L)

26.0(16.25~43)

21.5(14.5~44.0)

35.5(22.0~43.5)

0.200

AST (U/L)

22.0(17.0~29.0)

37.0(19.75~56.5)

37.5(23.5~54.25)

0.497

DBIL (umol/L)

2.1(1.6~3.0)

3.7(2.2~6.25)

2.8(1.7~4.5)

0.137

CKMB (U/L)

10.0(7.0~14.0)

15.0(10.0~23.0)

12.0(9.5~22.25)

0.519

IL-6 (ng/mL)

2.78(0.70~7.24)

15.1(6.9~82.3)

8.87(4.4~36.58)

0.279

Abbreviation: COVID-19: Coronavirus Disease 2019; IQR: Interquartile Range; PT: Prothrombin Time; PT-INR: International Normalized Ratio Of Prothrombin Time; CRP: C-Reactive Protein; PCT: Procalcitonin; LDH: Lactate Dehydrogenase; NLR: Neutrophil To Lymphocyte Ratio; DBIL: Direct Bilirubin; AST: Aspartate Amino Transferase; ALT: Alanine Aminotransferase; CK: Creatine Kinase; IL: Interleukin.