Table 4: Laboratory parameters of severe COVID-19 patients with or without hepatitis virus infection.
Variable (unit, normal range) |
Total (n = 50) |
With hepatitis virus infection (n = 24) |
without hepatitis virus infection (n = 26) |
P value |
Platelets (109/L) |
177.5(124.75~249.0) |
173.5(117.75~211.25) |
200.0(124.75~282.75) |
0.248 |
Lymphocytes (109/L) |
0.84(0.415~1.18) |
0.59(0.43~1.06) |
0.95(0.41~1.22) |
0.252 |
CD3+ T cells (count/uL) |
451(311.5~731.5) |
384.5(258.0~746.75) |
594.0(343.0~732.0) |
0.403 |
CD3+CD4+ T cells (count/uL) |
316.0(116.0~420.0) |
249.0(103.0~427.25) |
354.0(129.0~420.0) |
0.687 |
CD3+CD8+ T cells (count/uL) |
223.0(94.5~301.5) |
127.5(78.25~314.0) |
266.0(145.0~290.0) |
0.267 |
CD19+ B cells (count/uL) |
84(44~191.5) |
75.0(40.50~148.0) |
90.0(71.0~197.0) |
0.373 |
PT (s) |
12.4(11.8~13.56) |
13.0(11.9~13.9) |
12.3(11.75~13.05) |
0.173 |
PT-INR |
1.14(1.08~1.24) |
1.19(1.09~1.27) |
1.13(1.075~1.195) |
0.166 |
CRP ((mg/L)) |
32.7(8.05~95.44) |
29.47(6.81~97.79) |
32.7(8.5~97.5) |
0.803 |
PCT(ng/ml) |
0.05(0.05~0.14) |
0.05(0.05~0.07) |
0.095(0.05~0.81) |
0.078 |
LDH (U/L) |
282(199.5~449.75) |
292.0(200.5~456.5) |
269.0(191.5~442.0) |
0.831 |
NLR |
4.84(2.57~13.7) |
4.8(3.07~14.6) |
5.2(2.39~11.99) |
0.669 |
ALT (U/L) |
26.0(16.25~43) |
21.5(14.5~44.0) |
35.5(22.0~43.5) |
0.200 |
AST (U/L) |
22.0(17.0~29.0) |
37.0(19.75~56.5) |
37.5(23.5~54.25) |
0.497 |
DBIL (umol/L) |
2.1(1.6~3.0) |
3.7(2.2~6.25) |
2.8(1.7~4.5) |
0.137 |
CKMB (U/L) |
10.0(7.0~14.0) |
15.0(10.0~23.0) |
12.0(9.5~22.25) |
0.519 |
IL-6 (ng/mL) |
2.78(0.70~7.24) |
15.1(6.9~82.3) |
8.87(4.4~36.58) |
0.279 |
Abbreviation: COVID-19: Coronavirus Disease 2019; IQR: Interquartile Range; PT: Prothrombin Time; PT-INR: International Normalized Ratio Of Prothrombin Time; CRP: C-Reactive Protein; PCT: Procalcitonin; LDH: Lactate Dehydrogenase; NLR: Neutrophil To Lymphocyte Ratio; DBIL: Direct Bilirubin; AST: Aspartate Amino Transferase; ALT: Alanine Aminotransferase; CK: Creatine Kinase; IL: Interleukin.